Vitamin B-12 is commonly found in many foods from animals, especially liver, kidney, fish and shellfish, meat, and dairy foods
A quick intramuscular injection in the thigh, twice a week
Because of its short and variable half-life and its context-dependent activity profile, many published protocols time the dose close to the desired observation window, often in the evening
This slowed motility, combined with reduced food intake and often lower fiber and fluid consumption, creates the conditions for constipation
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Christofk HR, Vander Heiden MG, Harris MH, Ramanathan A, Gerszten RE, Wei R et al