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Banki K, Hutter E, Colombo E, Gonchoroff NJ, Perl A
Diabetes Metab Syndr Obes
Epithalon upregulates the expression of the catalytic subunit hTERT (human telomerase reverse transcriptase), leading to measurable telomerase activation
, it was found that when LD is used on UF-induced rats, the expression of IGF-I and PCNA mRNA were significantly reduced as compared to the model group, suggesting its ability to reduce leiomyoma cell proliferation via this mechanism
It was originally developed as an anti-obesity drug candidate because early research suggested it could stimulate lipolysis (fat breakdown) and reduce lipogenesis (fat formation) without the typical growth-promoting or IGF-1raising effects of full HGH
P =0.001)
