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Results showed that liraglutide treatment (50 nM) significantly reversed IL-1-induced increase in GAG release from the extracellular matrix of the chondrocytes ( p = 0.0227 compared with IL-1 alone) (Fig

There was no significant change in BMI within the exenatide group at 12 weeks, indicating that the effect on intracranial pressure was not driven by reduction in body weight, but likely by direct effect of exenatide to modulate intracranial pressure at the choroid plexus

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