It upregulates genes involved in collagen synthesis (COL1A1, COL3A1, COL5A1), extracellular matrix remodeling (decorin, fibromodulin), and antioxidant defense (superoxide dismutase, glutathione peroxidase) while simultaneously suppressing genes associated with inflammation (IL-6, TNF-alpha), fibrinogen production, and tissue destruction (several MMPs)
Another bile salts chemosensor is the nuclear farnesoid X receptor (FXR) (347) which activation, contrarily to TGR5, blocks the release of GLP-1 in the colonic L-cells (348), while in the liver induces glycogenesis helping to improve glucose homeostasis
From healthy detoxification processes and hormone support to mitochondrial function and healthy ageing, Broccoli Plus supports a wide spectrum of wellness goals in one small, convenient capsule
It is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus
Progestin-only pills, patches, rings, and intrauterine devices (IUDs) bypass oral absorption entirely and are considered safer choices if you're concerned about GLP-1 interference
Stable for 24+ months