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150 mcg subQ for 1-2 weeks, then 300 mcg
This commonly includes lifelong treatment for pernicious anaemia, managing severe B12 deficiency with neurological symptoms to prevent further damage, and for individuals post-gastric surgery due to impaired absorption
For a full breakdown of how AOD 9604 works, check out our companion article
Second, an in vitro chromosome aberration assay was performed in Chinese Hamster Ovary (CHO) cells treated with AOD9604 (20, 50, 100, 200 g/mL) in the absence or presence of an S-9 metabolic activation system
Niacinamide does not cause the dramatic flush of niacin, so titration to mitigate flushing is usually not necessary
An insufficient level of B12 is medically considered a form of anemia, much like the anemia one would develop with low iron
