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A., Taylor, M

These cases collectively suggest a potential link between semaglutide use and the development or exacerbation of depressive symptoms, warranting closer monitoring in clinical practice

"It'll have the muscle-boosting, muscle-building effects, but it will promote fluid retention, it will promote osteoarthritis, inflammation, deranged glucose metabolism and increased diabetes risk if she's a susceptible person," she said

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Activation of PAR2 in human OA cartilage upregulated catabolic and pro-inflammatory pathways, resulting in cartilage degradation (110)

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