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If this occurs, slight dose adjustment (increasing by 50mcg if not already at 500mcg) may help

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(a ) Percent change in body weight from day 0, ( b ) body weight, and ( c ) food intake was measured up to 44 days

Hao J, Shen W, Tian C, Liu Z, Ren J, Luo C, Long J, Sharman E, Liu J: Mitochondrial nutrients improve immune dysfunction in the type 2 diabetic Goto-Kakizaki rats