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Wegovy is also started at a low dose of 0.25 mg
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Treatment with tesamorelin resulted in an increase from baseline in mean lean body mass of 1.3 kg in Study 1 and of 1.2 kg in Study 2, respectively (compared with a decrease of 0.2 kg in Study 1 and of 0.03 kg in Study 2, respectively, in patients receiving placebo)
Common adverse events included diarrhea, vomiting, and constipation (more common for those on the highest dose)
Summary There are many promising studies that show significant weight loss from monotherapy and combination therapy in patients with type 2 diabetes
Risk of Hypoglycemia: Although less common with GP1 medications compared to other diabetes treatments, there is still a risk of low blood sugar, especially when combined with other medications
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