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This is not directly caused by the medication but by metabolic changes during fat loss

3.2 Semaglutides pharmacological profile and the blood-brain barrier Semaglutide is a GLP-1 analog with approximately 94% homology to human GLP-1

Women using oral contraceptives should be counseled about this potential interaction and may need to consider alternative or additional contraceptive methods, particularly during the initial weeks of treatment when gastric emptying effects may be most pronounced

Retrieved from Yao, H., Zhang, A., Li, D., et al

This excess risk stems from multiple factors including accelerated atherosclerosis, increased inflammatory state, abnormal blood clotting tendencies, and the metabolic damage caused by chronic hyperglycemia

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