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Research subjects microsomal glutathione S-transferase

[1] [3] Humans synthesize carnitine from the substrate TML (6- N -trimethyllysine), which is in turn derived from the methylation of the amino acid lysine

This substance is combined with carnitine to form acetyl-carnitine via carnitine palmitoyltransferase I

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Growth/differentiation factor-15 (GDF-15) Another potential therapeutic pathway for obesity pharmacotherapies is through the stress-induced cytokine GDF-15, which is expressed in multiple cell types including cardiomyocytes, adipocytes and macrophages [98]

10.15386/cjmed-804 19 ChoI