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In mast cells, lipophilic dihydroxy BAs (such as CDCA and DCA as well as their glycine and taurine conjugates) directly activate mast cells, leading to histamine release

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Ipamorelin, acting on a separate ghrelin-receptor pathway, can amplify that release while remaining relatively selective

Zinc is a cofactor in over 300 enzymes and many important biological processes, such as DNA, gene expression, nutrient utilization, protein absorption, and collagen formation

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