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The likelihood of stroke occurrence is up to twofold higher in people with T2D compared with those without T2D [1, 2]
Just recently there was a, a big analysis, and I think that found that GLP-1 drugs were linked to a higher risk of skeletal disorders, so things like osteoporosis
GLP-1 improves insulin function to lower blood sugar levels and delay gastric emptying, decreasing appetite
Experiences differ
From a vertical perspective, these mechanistic differences correspond to specific outcome domains: incretin-dominant agents optimize glycemic endpoints, glucagon-dominant agents improve hepatic and energy balance parameters, and balanced tri-agonists bridge both dimensions
Lancet Neurol 14(3):329340 Biessels GJ, Verhagen C, Janssen J et al (2019) Effect of linagliptin on cognitive performance in patients with type 2 diabetes and cardiorenal comorbidities: the CARMELINA randomized trial
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