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Against this background, this review examines GLP-1RA-associated changes in eating experience as a multilevel biological phenomenon rather than a uniform taste disorder. We use a sensorylikingwanting framework to organise evidence across peripheral taste signalling, brainstem interoceptive integration, and central reward-related pathways

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For those combining semaglutide with other compounds like B12 , glycine , or L-carnitine , the additional ingredients in combined preparations may contribute to or modify injection site reaction patterns

Karges gratefully acknowledges the financial support provided by the Liebig fellowship from the Chemical Industry Fund of the German Chemical Industry Association, the Life Sciences Bridge Award from the Aventis Foundation, and the Paul Ehrlich & Ludwig Darmstaedter Early Career Award 2024 a prize awarded by the Paul Ehrlich Foundation, Germany

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