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Int J Mol Sci,
Metformin inhibits the NLRP3 inflammasome via AMPK/mTOR-dependent effects in diabetic cardiomyopathy
2011 Sep;17(9):82733
This paper extends prior efforts to clarify the mechanisms underlying the protective effect of dietary energy restriction on neoplastic growth, documenting changes in gene expression within tumours as a function of host diet
Telomere lengthening has not been demonstrated in a large, prospective human trial
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