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Studies conducted in mouse models of DMD have suggested that Receptor Grade IGF-1 LR3 and other IGF-1 derivatives may overcome the adverse impacts of Myostatin to protect muscle cells and prevent apoptosis

IGF-1R Binding and Downstream Signalling IGF-1 LR3 remains a full agonist of the IGF-1 receptor, with very low affinity for IGFBPs making it more potent than unmodified IGF-1 in cell culture and pre-clinical models

Phytochemistry 55(3):213216 Pedras MSC, Zheng QA (2010) Metabolic responses of Thellungiella halophila/salsuginea to biotic and abiotic stresses: metabolite profiles and quantitative analyses

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