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doi: 10.1016/j.schres.2014.03.005 186 WangAKMillerBJ
D., & Corr, L
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10.1016/j.cmet.2018.03.001 31
IGF-1 LR3 (Long R3 Insulin-Like Growth Factor 1) is a synthetic, lengthened analogue of human IGF-1 , designed to exhibit greater metabolic stability and reduced binding to IGF-binding proteins (IGFBPs)
The prodrug exhibited notable in vitro inhibition against MDA-MB-231 and DU145 under 3% O 2 hypoxic conditions
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