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Importantly, dulaglutide showed reduced major adverse cardiovascular events (MACE) in the REWIND trial, making it another GLP-1 RA with proven cardiovascular benefit
Food and Drug Administration (9)
The choice of alternative therapy depends on individual patient factors including renal function, cardiovascular risk profile, weight management goals, hypoglycaemia risk, and patient preferences, all of which should be discussed thoroughly with the GP or diabetes specialist team
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That is one reason GLP-1 and GIP medications have become part of the conversation for some patients: by helping reduce appetite, improve blood sugar control, and support meaningful weight loss, they may offer an added tool for people whose thyroid treatment alone has not solved the weight struggle
Semaglutide is the same active ingredient used in three products marketed by Novo Nordisk: Ozempic, Rybelsus, and Wegovy
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