[64], treatment with acetyl-l-carnitine (500 mg twice daily intramuscularly for 10 days followed by 2000 mg daily administered orally for 355 days) resulted in improvement in neurophysiological parameters and pain reduction over a 1-year period [64]
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Insulin Resistance: Chronic, high-dose use can downregulate insulin receptors, potentially leading to long-term insulin resistance and elevated fasting glucose
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IGF Res