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Resulting concentration: 200 mg/mL
9,13 GSH repletion not only provides surplus cysteine as an energy substrate for the Krebs cycle, it also serves the important role of scavenging for free radicals and peroxynitrite
Some discontinued clinical trials (for example in postoperative ileus) failed to demonstrate sufficient efficacy in primary endpoints, although certain biological signaling effects remained measurable and scientifically relevant
Supplementation is recommended only when deficiency is documented or to protect bones during hormone therapy
However, in long-term studies or with predisposed subjects, this is a formidable variable that must be tracked