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The defining 2018 Biochemical Pharmacology study reported a methylquinolinium NNMT inhibitor reducing body weight, white-fat mass and adipocyte size in diet-induced obese mice without changing food intake, while raising intracellular NAD+ and SAM [1]
Vasavada A, Patel P, Sanghavi DK
Not approved for human or veterinary use
Both units are used, but mcg is more common for B12 doses, mainly for smaller amounts
Low B12 doesnt directly cause weight gain, but chronic fatigue and slow metabolism from a deficiency may lead to reduced activity levels, contributing to weight gain over time
They do this by adding certain foods to their diet
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