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Animal studies have shown adverse fetal outcomes with GLP-1 agonists

The active substance is semaglutide

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doi: 10.1016/S0891-5849(00)00280-X 58 CoxP

We designed an optimized LNP by replacing cholesterol with equal amount of -sitosterol, which was defined as the X% LNP (X% is the ratio of -sitosterol to LNP)

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