Fermentable fibers can raise the bodys own GLP-1 through short-chain fatty acid signaling and improve satiety and glucose control, but their standalone weight-loss effect is small, on the order of 0.3 to 0.8 kg versus control, compared with 10 to 20 kg or more for the drugs
Treatment adherence is improving: persistence improved from ~40% for those starting treatment in 2023 to 63% for those beginning in early 2024 (one-year continuation)
Ultrasound assisted extraction of polysaccharides from Lentinus edodes and its anti-hepatitis B activity in vitro
In the event of shortages, the United States Food and Drug Administration allows certain manufacturers to prepare similar compounded versions of drugs, like those sold by Hims & Hers
Very high oral doses can cause nausea, cramping, or a fishy body odor
ranges from around $900 to $1,400 per month