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Search terms included combinations of GLP-1 receptor agonists, metformin, inositol, PCOS, and randomized controlled trial, with Boolean operators and MeSH-aligned phrasing adapted to each database
The Conservative 16-Week Escalation For individuals with a history of sensitivity to GLP-1 medications, previous GI issues, or a general preference for caution, a slower escalation stretches the timeline to 16 weeks or longer
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For years, options were limited to basic dietary changes or early-generation metabolic therapies
