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The SUSTAIN clinical trial program, which evaluated semaglutide for type 2 diabetes, provides robust evidence regarding its effects on cholesterol and other lipid parameters

If you experience any persistent or concerning symptoms, contact your GP or diabetes specialist nurse for guidance

Third, the approval of orforglipron signals that non-peptide small molecules can replicate peptide receptor pharmacology, potentially disrupting the peptide therapeutics market for some targets

However, if you experience mild stomach cramping or nausea, taking it with a small meal can help prevent discomfort

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