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The balance of the different CRP isoforms, monomeric (mCRP) or native pentameric (nCRP) within the plaque determines the preponderance of a proinflammatory or anti-inflammatory effect, respectively (165)

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In patients without oxidative stress markers, excessive supplementation may impair immune functioning

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55 World Health Organization (2017) Guideline: Alternative mass drug administration regimens to eliminate lymphatic Filariasis World Health Organization