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[12] It even helped to increase mobility in chronically stressed rats in that study
On top of this, cells dont seem to retain cyanocobalamin as well as some of the other forms (18)
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Research shows that in senescent cells, p53 levels are maintained low through ubiquitination while its pro-apoptotic activity is repressed through nuclear segregation by FOXO4. The peptide's competitive inhibition restores p53 activity by promoting nuclear exclusion, allowing p53 to execute its pro-apoptotic program and eliminate senescent cells through targeted pathway activation
Feldmann, M
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