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If your body aches seem to get worse every time your dose goes up, let your doctor know

Metabolic improvements beyond weight, including blood sugar normalization and reduced inflammation, become measurable in lab work

When you lose weight quickly, as is common with semaglutide, your body may enter a state of stress, pushing more hair follicles into the shedding phase of the hair growth cycle

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All in all, the placebo group fared far worse than those on orforglipron