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[3] [1] Semaglutide carries a boxed warning about thyroid C-cell tumors observed in rodent studies (though human relevance remains uncertain) and is contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

Very heavy meals can worsen nausea

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Patients who underwent cholecystectomy for acute cholecystitis or symptomatic cholelithiasis typically have uncomplicated courses, while those with biliary dyskinesia or postcholecystectomy syndrome may need closer attention

Infract size in sham-operated rats was 0.60.04 and significantly increased infarct size in cigarette smoke-exposed rats with MI was observed compared to tobacco-nave rats (45.72.1 vs 37.60.56