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In addition, GLP-1 can also inhibit the identity loss and dysfunction of pancreatic islets cell ( PC1/3 and PC2 are neuroendocrine specific endoproteases belonging to the subtilisin-like serine protease family
J Am Geriatr Soc 73(9):2647-2976
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The tissue distribution results showed that the radioactivity intensity in most tissues peaked 1 h after administration, which was slightly later than the peak time of the total radioactivity concentration in plasma (0.167 h)
These observations in the past have made GIP unattractive as a therapeutic agent for T2D
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