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Therapeutics with enhanced efficacy, improved pharmacokinetics (PK) allowing less-frequent dosing and good tolerability remain in high demand to address the unmet medical need of patients with obesity

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It triggers the release of norepinephrine, a neurotransmitter that suppresses appetite and increases energy levels

Compared to tirzepatide , orforglipron offers the convenience of oral administration but may not achieve the same degree of efficacy

If you are experiencing any combination of these symptoms while on GLP-1 therapy, speak with your provider about checking your serum B12 levels

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