Among women with PCOS, semaglutide or tirzepatide prescribing increased from 2.4% in 2021 to 17.6% in 2025, a more than 7-fold increase
The biggest concern around the safety of microdosing is if patients are doing it without the knowledge of their treating team (such as their GP, dietitian, and pharmacist)
At this time horizon, clinical benefits with oral semaglutide 14 mg were reduced and incremental costs were increased, yielding an ICER of GBP 21,821 per QALY gained versus empagliflozin 25 mg
This observed risk profile likely stems from two pharmacological factors: (1) the contraindication of metformin in patients with renal insufficiency, and (2) the potential dehydrating effects associated with GLP-1 receptor agonists
It occurs naturally in your blood plasma, and your body produces less of it as you age, dropping from roughly 200 ng/mL at age 20 to about 80 ng/mL by age 60
Are there injection site side effects I should expect, even with proper technique