what are the negatives of glp 1 GLP-1 medications like Ozempic, Wegovy and Mounjaro changing diabetes and weight management, but they aren't recommended during pregnancy or while nursing. current recommendation is to stop before conception and discuss Eating Well on Your GLP-1

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Firstly, there is an urgent need for extended follow-up studies that last longer than current trial lengths to assess the long-term safety and efficacy of therapies over a decade or more

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The factors contributing to bone impairment in individuals with PWS are not fully understood, but possible explanations include loss of function of genes in the q11-q13 region of the paternal copy of chromosome 15, reduced production of sex hormones during puberty, as well as a relative GHD during childhood and adolescence (79)

In this issue of Plant Physiology , Speiser et al