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Blood chemistry panels showed no hepatotoxicity (ALT, AST, bilirubin all within normal limits), no nephrotoxicity (creatinine, BUN unchanged), and no hematologic changes
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The GLP-1 receptor activation in the hypothalamus is reaching concentrations that meaningfully alter appetite signaling
It is a tolerability phase: the body learns to process the medication without the side effects that accompany higher doses
These hormones are normally released in the gut after eating and play an important role in appetite regulation and energy balance
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