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Un ambiente testicular alterado (con presencia de leucocitos, clulas germinales inmaduras, etc.) puede causar disfuncin en la espermatognesis

[...] Even though the carboxylic acid valproate (VPA) is an HDACi with weak inhibitory potential, it is an interesting drug for clinical trials due to its well-characterized pharmacodynamic and pharmacokinetic profile (see Table 6)

Skin Reactions: A small number of individuals report minor skin itching or bumps, which are usually transient and mild

Wilding, J