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(2010, September 1)

Gastrointestinal Adverse Reactions In the pool of placebo-controlled trials, gastrointestinal adverse reactions occurred more frequently among patients who received RYBELSUS than placebo: RYBELSUS 14 mg once daily (41%), RYBELSUS 7 mg once daily (32%) and placebo (21%), including severe reactions (RYBELSUS 14 mg 2.0%, RYBELSUS 7 mg 0.6%, placebo 0.3%)

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Fatigue is another reported effect

OGrady K, Grabrucker AM (2025) Metal dyshomeostasis as a driver of gut pathology in autism spectrum disorders

doi: 10.1186/1750-1326-2-9 67 Gonzlez De AguilarJ