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Vitamin A (retinol) downregulates the receptor for advanced glycation endproducts (RAGE) by oxidant-dependent activation of p38 MAPK and NF-kB in human lung cancer A549 cells

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Local injection site reactions are the most common form of hypersensitivity and may include: Erythema, swelling, or induration at the injection site Pruritus or burning sensation localized to the area Persistent pain or tenderness beyond typical injection discomfort Development of nodules or persistent lumps These reactions typically occur within hours to days of injection and may resolve spontaneously, though persistent or worsening symptoms warrant medical evaluation

Retrieved from Jouanne, M., Oddoux, S., Nol, A., et al