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But as MOTS-c improves metabolic health, reduces body weight, and enhances insulin sensitivity, your blood pressure may naturally improve

First-line management includes drinking 1.52 litres of fluids daily, using paracetamol (maximum 4 g daily) or ibuprofen (maximum 1.2 g daily for over-the-counter use) as appropriate, and resting in a quiet environment

These benefits from once-weekly subcutaneous semaglutide were demonstrated in the multicentre, placebo-controlled ESSENCE trial

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Neither is necessarily "better" than the other

they are, "raised blood pressure", "overweight/obesity", "hyperglycemia (high blood glucose levels)" and "hyperlipidemia (high levels of fat in the blood)" [1]