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JAMA 325 , 14031413 (2021)
Some research suggests that an imbalance in gut bacteria may contribute to certain types of constipation, including irritable bowel syndrome with constipation (IBS-C) ( Taking probiotic supplements may help support a balanced gut microbiome
Other organisms such as Helicobacter pylori (responsible for ulcers and cases of severe heartburn) or giardia (a parasite) can also eat away at the intestinal lining
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Increasing the endogenous secretion of GLP-1 The apical surface of L-cells in the intestinal lining plays a critical role in sensing luminal compounds such as carbohydrates, proteins, gut microbiota, bacteria-derived molecules, bile acids, lipids, fatty acids, and polyphenols
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