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The originally identified activity was called retinaldehyde reductase
However, as cancer progresses, this stress-relieving property of autophagy is utilized by tumor cells to meet their extensive metabolic and nutritional requirements necessary for proliferation and survival
doi: 10.1073/pnas.86.19.7606 119 LiQ-XGaoHGuoY-XWangBYHuaRXGaoLet al
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IGF-1 LR3 (IGF-1 long R3) is a fusion protein that include in the amino terminus the first 11 amino acids of methionyl porcine growth hormone and the IGF1 sequence, where Glu3 was substituted by Arg
Test compounds (final concentration 10 M) were added with a 50-nl pin tool and the plates were incubated for 30 min at 20 C
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