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Sometimes a brief waiting period resolves this

As we age, NAD+ levels decline significantly, contributing to fatigue, metabolic slowdowns, and cellular aging

Reasons for increased needs in athletes: stress related to physical demands (Yes, training is stress on the body!) biological adaptations increased turnover (athletes use more vitamins) genetics reduced absorption Early detection of deficiency can be difficult to recognize because symptoms overlap with many other conditions and are normalized in athletes

But the full picture is more nuanced than that

dissolving 5 mg in 2 mL of diluent yields a working stock of 2.5 mg/mL (2500 g/mL), and adjusting the diluent volume scales the concentration proportionally for a given assay

If they start to dip, it might be time to increase their frequency for a bit