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We previously showed that GIPR activity in alpha cells potentiates amino-acid-stimulated glucagon secretion in mouse islets 11 , and here we found the same interaction between hGIP and amino acids in human islets using concentrations of amino acids found in the postprandial state (Extended Data Figure 4) 11 , prompting us to ask whether tirzepatide engagement of the GIPR in human islets also enhances the effect of amino acids on glucagon secretion

Lets stop referring to them as weight loss meds and focus on metabolic health as a broader concept

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Investigators analyzed 132 randomized controlled trials, enrolling 48,209 adults with overweight or obesity

Flushes Out Toxins & Waste When youre on a weight loss program, your body breaks down fat cells, releasing stored toxins