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Recent advances have begun to redefine IIH as a probable metabolic disease involving a range of systemic manifestations

Histopathology Complete histopathology was performed in 24-mo-old female [Old Con ( n = 16), and Old mAb ( n = 16)] and male mice [Old Con ( n = 15), and Old mAb ( n = 17)] following 6 mo of mAb treatment, as well as in female mice at death from the longevity study [Old Con ( n = 30), and Old mAb ( n = 20)]

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The Neostigmine Interaction (Panel 4) : The infographic highlights the Neostigmine Paradox: administering neostigmine inhibits plasma pseudocholinesterase, the very enzyme that metabolizes succinylcholine, which can therefore dangerously intensify and prolong the neuromuscular blockade rather than reversing it

Nat Protoc 5 , 5166 (2010)