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At the same time, it has a similar function to GPX7, which can increase the PDI activity of ER redox protein 1 (ERO1), promote the oxidative folding of endoplasmic reticulum proteins, and reduce oxidative stress (Raykhel et al., 2007)

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Accordingly, the disadvantage of these models is the absence of a simple way to assess barrier function such as TEER measurement and complicated permeability screening (Cho et al., 2017)

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Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity