This information is provided for educational purposes and should not be interpreted as medical advice or an endorsement of any specific medication
To get approved, your client must meet one of the following criteria: BMI of 35 or higher: Automatically qualifies for weight-loss coverage without needing a secondary health condition
Mood Enhancement The relationship between B12 and mental wellbeing is well-established: B12 is involved in producing and regulating serotonin and dopamine It supports overall neurotransmitter balance Deficiency is linked to depression, anxiety, and mood instability Optimal levels help maintain emotional resilience While not a treatment for clinical depression, many clients experience improved mood stability and outlook with regular B12 injections
10.1016/j.cell.2018.10.001 47 KalamkarS.AcharyaJ.Kolappurath MadathilA.GajjarV.DivateU.Karandikar-IyerS.et al (2022)
Mechanisms deciphered in these studies indicate that the interaction between serotonin and GLP-1 in the hindbrain increases proopiomelanocortin/cocaine- and amphetamine-regulated transcript (POMC/CART) neuron activity, leading to induction of satiety signals and suppression of neuropeptide Y/agouti-related peptide (NPY/AgRP) neuron activity, which in turn suppresses hunger
Those are useful, but there are serious limitations regarding how benefits to animals can be translated to benefits to people