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NNMT is a cytosolic S-adenosyl-L-methionine-dependent methyltransferase that converts nicotinamide to 1-methylnicotinamide, spending SAM and diverting nicotinamide away from the NAD+ salvage pathway
Authors contributions All authors participated in the round table discussion on which the article is based
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The erratic nerve signaling that causes the rapid heart rate and blood pressure swings in POTS is worsened by the lack of antioxidant protection in the central nervous system
J Clin Endocrinol Metab 103(1):288294
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