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Curr Neuropharmacol 2009
GSH can directly quench free radicals and ROS while also serving as a cosubstrate for GPX in the conversion of hydrogen peroxide (H2O2) and lipid peroxide (Lipid-OOH) into water and lipid alcohol (Lipid-OH), respectively
Exercise provides the stimulus that tells the body to maintain muscle tissue rather than catabolizing it
Although Agrp and Pomc are predominantly expressed in hypothalamic nuclei, emerging evidence suggests that these neuropeptides or their mRNA may also be detected in mesocorticolimbic regions, either due to local expression or via projections from hypothalamic neurons [87,88,89,90,91]
However, the review noted that studies in truly alcohol-dependent animals remain limited, and many models have focused on reinforcing effects rather than continued drinking despite negative consequences