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found that Receptor-interacting protein 2 (RIP2) can regulate cartilage degradation and oxidative stress in IL-1 -treated chondrocytes by regulating TRAF3 expression and p38-MAPK pathway activation (Pan et al., 2021)

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[4] While occasional mild leg cramps may not require immediate medical attention, certain features warrant prompt evaluation by your healthcare provider to rule out more serious underlying conditions or complications

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