Problems with this type of study include selection bias and confounding variables
:Basic cofactors consist of: Vitamins A and Vitamin D (11,000 IU and 3000 5000 IU respectively) Vitamin C at 4000+ mg per day Vitamin E B vitamin complex with P5P, biotin and pantethine (without including cyano B12 or folic acid) A 1:1 magnesium:calcium supplement Zinc, 50 mg per day Omega 3 fatty acids, 2-6 caps per day Optional Basic Cofactors include: Glycophospholipids Additional pantethine Multimineral supplements (choline, selenium) Alpha lipoic acid D-Ribose CoQ-10 Titrate B12s while adjusting methylfolate and potassium Methylcobalamin (MeB12) should start at 15-20 mg per day Adenosylcobalamin (AdoB12) should start at 10 mg per week Titrate methylfolate to sufficiency, starting at 1 mg Titrate L-carnitine fumarate (LCF) to effectiveness, starting at 125 mg per day and aiming for 500-1000 mg per day, stopping when an increase of 250 mg makes no difference
Most patients report improvement after 4-8 weeks as their hypothalamus recalibrates to the new metabolic baseline
The oral form may serve as a starting option for someone strongly averse to needles or with more modest goals
Suspected side effects should be reported via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)
Not everyone can use Mounjaro safely