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Attenuation of glomerular hyperfiltration results in prevention of long-term glomerular damage, contributing to reduce the progression of diabetic kidney disease (DKD) (41)
Toxic amounts of peroxides and free radicals produced in the cells are scavenged by the selenium-containing enzyme glutathione peroxidase
10.1136/bmjdrc-2019-000783 185 YangX.QiangQ.LiN.FengP.WeiW.HlscherC
However, treatment with JMJD3 and UTX inhibitor GSKJ4 did not reduce AMPK and YBX1 levels (Extended Data Fig
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Dzik KP, Kaczor JJ
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