Use with caution in pregnant animals
For example, in the STEP 1 trial , patients taking semaglutide lost an average of 14.9% of their body weight over 68 weeks , compared with just 2.4% in the placebo group (NEJM study)
Methionine and choline help support overall liver health, not just fat metabolism
For the maintenance treatment of vitamin B12 deficiency, the usual dose is 60-100mcg SC/IM, given once per month
These are one of, if not the most rigorously studied class of peptides ever, with many large, placebo-controlled, randomized trials that followed over the past twenty years from the original GLP-1 drugs such as exenatide, approved by the FDA in 2005
It helps regulate glycogen, which impacts energy levels